sars cov in 3 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T12839	SARS-CoV-IN-3		Others
	SARS-CoV-IN-3 is an effective SARS-CoV replication inhibitor.		Others
T60538	SARS-CoV-2-IN-14	3',5-Dichlorosalicylanilide	SARS-CoV
	SARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 μM), which is an analogue of niclosamide. SARS-CoV-2-IN-14 was more stable than niclosamide in the determination of human plasma and liver S9 enzym...		SARS-CoV
T78725	SARS-CoV-2 nsp14-IN-3		SARS-CoV
	SARS-CoV-2 nsp14-IN-3 (4975) is a potent inhibitor targeting the N7-Methyltransferase activity of SARS-CoV-2 nonstructural protein 14 (Nsp14), with an IC50 value of 3.5 μM [1].		SARS-CoV
T63679	SARS-CoV-2 3CLpro-IN-3
	SARS-CoV-2 3CLpro-IN-3 is a SARS CoV-2 3CLpro inhibitor that exhibits antiviral, antibacterial, and antifungal effects.
T62375	SARS-CoV-2 nsp13-IN-3
	SARS-CoV-2 nsp13-IN-3 (Compound C3) is a small molecule inhibitor of SARS-CoV-2 non-structural protein 13 (nsp13) that acts on nsp13 ssDNA+ATPase (IC50: 32 μM).
T8498	EIDD-1931	Beta-d-N4-hydroxycytidine	Virus Protease , HCV Protease , SARS-CoV , Topoisomerase
	EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells, Middle East respiratory syndr...		Virus Protease , HCV Protease , SARS-CoV , Topoisomerase
T60095	CCF0058981		SARS-CoV
	CCF0058981 (CCF981) is a 3-chlorophenyl analogue, serving as a noncovalent inhibitor of SARS-CoV-2 3CL pro (SC2), demonstrating potent activity with an IC50 of 68 nM. It also exhibits inhibitory effects against SARS-CoV-...		SARS-CoV
T60686	SARS-CoV-2 Mpro-IN-1
	SARS-CoV-2 Mpro-IN-1 (compound 16b-3) is a potent, selective and irreversible SARS-CoV-2 main protease (Mpro) inhibitor (IC 50 = 116 nM) [1].
T63694	SARS-CoV-2-IN-33
	SARS-CoV-2-IN-33 is an inhibitor of COVID-19. SARS-CoV-2-IN-3 exhibits good binding affinity (-8.0 Kcal/mole) for COVID-19 major protease (Mpro) (PDB ID: 6LU7). SARS-CoV-2-IN-33 exhibits good anti-proliferative effects o...
T79245	SARS-CoV-2-IN-45		SARS-CoV
	SARS-CoV-2-IN-45 (Compound 8p) serves as an inhibitor of SARS-CoV-2, effectively hindering viral replication in Calu-3 cells with an EC50 value of 0.5 μM and exhibiting negligible cytotoxic effects [1].		SARS-CoV
T62829	SARS-CoV-2 nsp14-IN-1
	SARS-CoV-2 nsp14-IN-1 (Compound 3) is a typical dual-substrate inhibitor of SARS-CoV-2Nsp14 Mtase (IC50: 0.061 μM). Histone lysine, protein arginine, DNA and RNA, etc.).
T81209	SARS-CoV-2-IN-62		SARS-CoV
	SARS-CoV-2-IN-62 (Compound R3b) effectively inhibits SARS-CoV-2 replication in Vero E6 and Calu-3 cells, demonstrating low cytotoxicity and EC50 values of 2.97 μM and 3.82 μM, respectively [1].		SARS-CoV
T79244	SARS-CoV-2-IN-44		SARS-CoV
	SARS-CoV-2-IN-44, an inhibitor of SARS-CoV-2, effectively suppresses viral replication with an EC50 value of 0.6μM and exhibits negligible cytotoxicity in Calu-3 cells, rendering it suitable for antiviral research [1].		SARS-CoV
T81206	SARS-CoV-2-IN-65		SARS-CoV
	SARS-CoV-2-IN-65 (compound 2f (81)) is a potent, orally active reversible inhibitor of SARS-CoV-2 entry, primarily obstructing the RBD:ACE2 interaction and TMPRSS2 activity within the ACE2-dependent pathway in Calu-3 cel...		SARS-CoV
T72451	SARS-CoV-2 Mpro-IN-6
	SARS-CoV-2 Mpro-IN-6 is a selective, covalent, and irreversible inhibitor of SARS-CoV-2 main protease (Mpro), exhibiting an inhibition concentration (IC50) of 0.18 μM. It does not inhibit human cathepsins B, F, K, and L ...
T81208	SARS-CoV-2-IN-63		SARS-CoV
	SARS-CoV-2-IN-63 (Compound R3e) serves as an inhibitor of SARS-CoV-2 replication, demonstrating low cytotoxicity. It effectively suppresses viral replication within Vero E6 cells and Calu-3 cells, yielding half-maximal e...		SARS-CoV
T73963	Hydroxychloroquine Impurity E
	Hydroxychloroquine Impurity E, an impurity found in Hydroxychloroquine, a synthetic antimalarial compound that also inhibits Toll-like receptor 7/9 (TLR7/9) signaling, has been shown to effectively inhibit SARS-CoV-2 inf...
T38174	Mpro inhibitor N3 hemihydrate
	Mpro inhibitor N3 hemihydrate is a potent antagonist of the SARS-CoV-2 main protease (Mpro), demonstrating an EC50 of 16.77 μM against SARS-CoV-2. It exhibits specific inhibition of Mpro in a range of coronaviruses, incl...
T69035	Camostat free base
	Camostat, also known as FOY 305, is a serine protease inhibitor. Camostat is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or...
T73964	Hydroxychloroquine Impurity F
	Hydroxychloroquine Impurity F, an impurity in Hydroxychloroquine, is identified in the synthetic antimalarial agent known for its capability to inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Additionally, Hydroxychlo...